Home

Fage otce Leštěno rozšířit lin et al 2017 bioorganic med chem nf kappa b kosit Detailní Agresivní

Structure-Based Design of Tricyclic NF-κB Inducing Kinase (NIK) Inhibitors  That Have High Selectivity over Phosphoinositide-3-kinase (PI3K) | Journal  of Medicinal Chemistry
Structure-Based Design of Tricyclic NF-κB Inducing Kinase (NIK) Inhibitors That Have High Selectivity over Phosphoinositide-3-kinase (PI3K) | Journal of Medicinal Chemistry

Synthetic Approaches to the New Drugs Approved During 2017 | Journal of Medicinal  Chemistry
Synthetic Approaches to the New Drugs Approved During 2017 | Journal of Medicinal Chemistry

Molecules | Free Full-Text | 2-Phenethylamines in Medicinal Chemistry: A  Review
Molecules | Free Full-Text | 2-Phenethylamines in Medicinal Chemistry: A Review

Molecules | Free Full-Text | Boron Chemicals in Drug Discovery and  Development: Synthesis and Medicinal Perspective
Molecules | Free Full-Text | Boron Chemicals in Drug Discovery and Development: Synthesis and Medicinal Perspective

Molecules | Free Full-Text | Pharmacotherapeutics Applications and Chemistry  of Chalcone Derivatives
Molecules | Free Full-Text | Pharmacotherapeutics Applications and Chemistry of Chalcone Derivatives

Exploring the structural and functional requirements of Phyto-compounds and  their synthetic scaffolds as anticancer agents: Medicinal chemistry  perspective - ScienceDirect
Exploring the structural and functional requirements of Phyto-compounds and their synthetic scaffolds as anticancer agents: Medicinal chemistry perspective - ScienceDirect

Discovery of Novel Small-Molecule Inhibitors of NF-κB Signaling with  Antiinflammatory and Anticancer Properties | Journal of Medicinal Chemistry
Discovery of Novel Small-Molecule Inhibitors of NF-κB Signaling with Antiinflammatory and Anticancer Properties | Journal of Medicinal Chemistry

Protein‐Templated Fragment Ligations—From Molecular Recognition to Drug  Discovery - Jaegle - 2017 - Angewandte Chemie International Edition - Wiley  Online Library
Protein‐Templated Fragment Ligations—From Molecular Recognition to Drug Discovery - Jaegle - 2017 - Angewandte Chemie International Edition - Wiley Online Library

The Cravatt Lab
The Cravatt Lab

Nonconjugated Hydrocarbons as Rigid‐Linear Motifs: Isosteres for Material  Sciences and Bioorganic and Medicinal Chemistry - Locke - 2019 - Chemistry  – A European Journal - Wiley Online Library
Nonconjugated Hydrocarbons as Rigid‐Linear Motifs: Isosteres for Material Sciences and Bioorganic and Medicinal Chemistry - Locke - 2019 - Chemistry – A European Journal - Wiley Online Library

Are We Opening the Door to a New Era of Medicinal Chemistry or Being  Collapsed to a Chemical Singularity? | Journal of Medicinal Chemistry
Are We Opening the Door to a New Era of Medicinal Chemistry or Being Collapsed to a Chemical Singularity? | Journal of Medicinal Chemistry

Bioorganic & Medicinal Chemistry Letters | Vol 27, Issue 3, Pages 361-700  (1 February 2017) | ScienceDirect.com by Elsevier
Bioorganic & Medicinal Chemistry Letters | Vol 27, Issue 3, Pages 361-700 (1 February 2017) | ScienceDirect.com by Elsevier

Morpholine as ubiquitous pharmacophore in medicinal chemistry: Deep insight  into the structure-activity relationship (SAR) - ScienceDirect
Morpholine as ubiquitous pharmacophore in medicinal chemistry: Deep insight into the structure-activity relationship (SAR) - ScienceDirect

Scaffold Diversity Inspired by the Natural Product Evodiamine: Discovery of  Highly Potent and Multitargeting Antitumor Agents | Journal of Medicinal  Chemistry
Scaffold Diversity Inspired by the Natural Product Evodiamine: Discovery of Highly Potent and Multitargeting Antitumor Agents | Journal of Medicinal Chemistry

Structure-Based Discovery of New Antagonist and Biased Agonist Chemotypes  for the Kappa Opioid Receptor | Journal of Medicinal Chemistry
Structure-Based Discovery of New Antagonist and Biased Agonist Chemotypes for the Kappa Opioid Receptor | Journal of Medicinal Chemistry

Targeting Stimulator of Interferon Genes (STING): A Medicinal Chemistry  Perspective | Journal of Medicinal Chemistry
Targeting Stimulator of Interferon Genes (STING): A Medicinal Chemistry Perspective | Journal of Medicinal Chemistry

Molecules | Free Full-Text | Breakthroughs in Medicinal Chemistry: New  Targets and Mechanisms, New Drugs, New Hopes–5
Molecules | Free Full-Text | Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–5

Bioorganic & Medicinal Chemistry | From controlling chemical bonding to  deciphering and manipulating biological processes | ScienceDirect.com by  Elsevier
Bioorganic & Medicinal Chemistry | From controlling chemical bonding to deciphering and manipulating biological processes | ScienceDirect.com by Elsevier

Medicinal chemistry of indole derivatives: Current to future therapeutic  prospectives - ScienceDirect
Medicinal chemistry of indole derivatives: Current to future therapeutic prospectives - ScienceDirect

Molecules | Free Full-Text | Anti-Cancer Potential of Synthetic Oleanolic  Acid Derivatives and Their Conjugates with NSAIDs
Molecules | Free Full-Text | Anti-Cancer Potential of Synthetic Oleanolic Acid Derivatives and Their Conjugates with NSAIDs

Molecules | Free Full-Text | Chemistry and the Potential Antiviral,  Anticancer, and Anti-Inflammatory Activities of Cardiotonic Steroids  Derived from Toads
Molecules | Free Full-Text | Chemistry and the Potential Antiviral, Anticancer, and Anti-Inflammatory Activities of Cardiotonic Steroids Derived from Toads

Molecules | Free Full-Text | Chlojaponilactone B Attenuates  Lipopolysaccharide-Induced Inflammatory Responses by Suppressing  TLR4-Mediated ROS Generation and NF-κB Signaling Pathway
Molecules | Free Full-Text | Chlojaponilactone B Attenuates Lipopolysaccharide-Induced Inflammatory Responses by Suppressing TLR4-Mediated ROS Generation and NF-κB Signaling Pathway

Molecules | Free Full-Text | Synthesis and Evaluation of NF-κB  Inhibitory Activity of Mollugin Derivatives
Molecules | Free Full-Text | Synthesis and Evaluation of NF-κB Inhibitory Activity of Mollugin Derivatives

Design of Novel 3-Pyrimidinylazaindole CDK2/9 Inhibitors with Potent In  Vitro and In Vivo Antitumor Efficacy in a Triple-Negative Breast Cancer  Model | Journal of Medicinal Chemistry
Design of Novel 3-Pyrimidinylazaindole CDK2/9 Inhibitors with Potent In Vitro and In Vivo Antitumor Efficacy in a Triple-Negative Breast Cancer Model | Journal of Medicinal Chemistry

Targeting the Receptor for Advanced Glycation Endproducts (RAGE): A  Medicinal Chemistry Perspective | Journal of Medicinal Chemistry
Targeting the Receptor for Advanced Glycation Endproducts (RAGE): A Medicinal Chemistry Perspective | Journal of Medicinal Chemistry

Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone  Lysine Demethylase KDM1A/LSD1. Part 1: High-Throughput Screening and  Preliminary Exploration | Journal of Medicinal Chemistry
Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 1: High-Throughput Screening and Preliminary Exploration | Journal of Medicinal Chemistry